Current News

Science news, press releases, and lay coverage of oligodendrocyte research worth reading.

2026-09-02 · Science Translational Medicine

Fotio et al.: Metabolic reallocation in spinal cord oligodendrocytes drives chronic pain in mice through neuronal Abeta42 production

Mouse. After a paw injury, spinal oligodendrocytes switch from making myelin protein to making lipid, axons suffer, and neuronal amyloid-beta42 builds; blocking it prevented the pain becoming chronic.

2019-10-03 · Cell Stem Cell

Neumann et al.: Metformin restores CNS remyelination capacity by rejuvenating aged stem cells

Metformin restores the responsiveness of aged OPCs to differentiation signals, making age-related remyelination failure at least partly reversible.

2019-01-29 · Journal of Neuroscience

Rankin et al.: Selective estrogen receptor modulators enhance CNS remyelination independent of estrogen receptors

Bazedoxifene and related SERMs promote OPC differentiation and remyelination, and the effect does not run through the estrogen receptor.

2017-02-15 · Lancet Neurology

Cadavid et al.: Safety and efficacy of opicinumab in acute optic neuritis (RENEW)

Anti-LINGO-1 antibody missed its primary endpoint in the intention to treat group but showed a latency effect per protocol. The approach remains open.

From PubMed

Asking PubMed for every paper on the oligodendrocyte in this section.